Drug interactions
Fluoxymesterone + Insulin detemir
Severity: Moderate
Fluoxymesterone and Insulin detemir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgenic anabolic steroids such as fluoxymesterone can improve insulin sensitivity and lower blood glucose, increasing the chance of hypoglycemia in insulin-treated patients.
What this interaction means in plain words
Fluoxymesterone and Insulin detemir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Androgens alter glucose metabolism and insulin sensitivity, adding to insulin's glucose-lowering effect.
What to do
Monitor blood glucose when starting or stopping the androgen and reduce insulin detemir dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin detemir
Frequently asked questions
Can I take Fluoxymesterone with Insulin detemir?
MediHelp rates the interaction as moderate. Fluoxymesterone and Insulin detemir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgenic anabolic steroids such as fluoxymesterone can improve insulin sensitivity and lower blood glucose, increasing the chance of hypoglycemia in insulin-treated patients.
How serious is the interaction between Fluoxymesterone and Insulin detemir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping the androgen and reduce insulin detemir dose if hypoglycemia occurs.
What other medicines interact with Insulin detemir?
MediHelp also lists interactions of Insulin detemir with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin detemir page.
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