Drug interactions
Formoterol + Inotuzumab
Severity: Moderate
Formoterol and Inotuzumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inotuzumab ozogamicin is associated with QT interval prolongation, and formoterol may add to this through its own QT effects and potassium lowering. The combination increases the chance of clinically important arrhythmia.
What this interaction means in plain words
Formoterol and Inotuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation (pharmacodynamic), aggravated by beta-2 agonist induced hypokalemia.
What to do
Check ECG and electrolytes before starting and repeat periodically during treatment. Replace potassium and magnesium as needed, and consider a non-QT-prolonging alternative if risk factors are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Frequently asked questions
Can I take Formoterol with Inotuzumab?
MediHelp rates the interaction as moderate. Formoterol and Inotuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Inotuzumab ozogamicin is associated with QT interval prolongation, and formoterol may add to this through its own QT effects and potassium lowering. The combination increases the chance of clinically important arrhythmia.
How serious is the interaction between Formoterol and Inotuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes before starting and repeat periodically during treatment. Replace potassium and magnesium as needed, and consider a non-QT-prolonging alternative if risk factors are present.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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