Drug interactions
Formoterol + Thiothixene
Severity: Moderate
Formoterol and Thiothixene: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs may prolong the QT interval: thiothixene is an antipsychotic with arrhythmia risk, and formoterol can cause hypokalemia and QT effects. Combined use may raise the risk of ventricular arrhythmia, especially in patients with other risk factors.
What this interaction means in plain words
Formoterol and Thiothixene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-agonist induced hypokalemia potentially increasing arrhythmic risk.
What to do
Check baseline ECG and electrolytes in patients with cardiac risk factors, and correct potassium and magnesium. Monitor for palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Formoterol and Thiothixene, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Frequently asked questions
Can I take Formoterol with Thiothixene?
MediHelp rates the interaction as moderate. Formoterol and Thiothixene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs may prolong the QT interval: thiothixene is an antipsychotic with arrhythmia risk, and formoterol can cause hypokalemia and QT effects. Combined use may raise the risk of ventricular arrhythmia, especially in patients with other risk factors.
How serious is the interaction between Formoterol and Thiothixene?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with cardiac risk factors, and correct potassium and magnesium. Monitor for palpitations or syncope.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.