Drug interactions
Forskolin + Heparin
Severity: Moderate
Forskolin and Heparin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin activates adenylyl cyclase and raises cAMP in platelets, which inhibits platelet aggregation. This could add to the bleeding risk of heparin, though clinical data are lacking.
What this interaction means in plain words
Forskolin and Heparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Forskolin increases platelet cAMP, inhibiting aggregation and adding to heparin's effect.
What to do
Advise avoiding forskolin supplements during heparin therapy. Monitor for bleeding if it is used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Heparin
- Defibrotide + Heparin Contraindicated
- Heparin + Ketorolac Contraindicated
- Heparin + Oritavancin Contraindicated
- Acemetacin + Heparin Major
- Acetylsalicylic acid + Heparin Major
- Alteplase + Heparin Major
Frequently asked questions
Can I take Forskolin with Heparin?
MediHelp rates the interaction as moderate. Forskolin and Heparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Forskolin activates adenylyl cyclase and raises cAMP in platelets, which inhibits platelet aggregation. This could add to the bleeding risk of heparin, though clinical data are lacking.
How serious is the interaction between Forskolin and Heparin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding forskolin supplements during heparin therapy. Monitor for bleeding if it is used.
What other medicines interact with Heparin?
MediHelp also lists interactions of Heparin with, for example, Defibrotide, Ketorolac, Oritavancin. The full list is on the Heparin page.
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