Drug interactions
Ginkgo biloba + Ketorolac
Severity: Moderate
Ginkgo biloba and Ketorolac: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo extracts inhibit platelet-activating factor and have been linked to case reports of bleeding. Adding ketorolac, a potent antiplatelet NSAID, may raise the risk of serious bleeding.
What this interaction means in plain words
Ginkgo biloba and Ketorolac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antiplatelet effects through inhibition of platelet-activating factor (ginkgo) and COX-1 (ketorolac).
What to do
Advise patients to stop ginkgo before and during ketorolac therapy. Monitor for bleeding, particularly in perioperative patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Ginkgo biloba with Ketorolac?
MediHelp rates the interaction as moderate. Ginkgo biloba and Ketorolac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo extracts inhibit platelet-activating factor and have been linked to case reports of bleeding. Adding ketorolac, a potent antiplatelet NSAID, may raise the risk of serious bleeding.
How serious is the interaction between Ginkgo biloba and Ketorolac?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to stop ginkgo before and during ketorolac therapy. Monitor for bleeding, particularly in perioperative patients.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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