Drug interactions
Ginko biloba + Ketorolac intranasal
Severity: Moderate
Ginko biloba and Ketorolac intranasal: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ketorolac is a potent NSAID that inhibits platelet function and carries a bleeding warning, and intranasal use gives meaningful systemic exposure. Ginkgo may add to the bleeding tendency.
What this interaction means in plain words
Ginko biloba and Ketorolac intranasal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antiplatelet effect: reversible COX inhibition by ketorolac and PAF antagonism by ginkgo.
What to do
Advise patients to stop ginkgo while using ketorolac, and monitor for bleeding including GI and nasal bleeding.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Frequently asked questions
Can I take Ginko biloba with Ketorolac intranasal?
MediHelp rates the interaction as moderate. Ginko biloba and Ketorolac intranasal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ketorolac is a potent NSAID that inhibits platelet function and carries a bleeding warning, and intranasal use gives meaningful systemic exposure. Ginkgo may add to the bleeding tendency.
How serious is the interaction between Ginko biloba and Ketorolac intranasal?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to stop ginkgo while using ketorolac, and monitor for bleeding including GI and nasal bleeding.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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