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Drug interactions

Ginko biloba + Salicylates

Severity: Moderate

Ginko biloba and Salicylates: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Non-acetylated salicylates have weak antiplatelet effects, but at high doses can contribute to bleeding and GI irritation. Ginkgo may add slightly to the bleeding tendency.

What this interaction means in plain words

Ginko biloba and Salicylates can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Possible additive antiplatelet effect from PAF antagonism (ginkgo) and prostaglandin inhibition (salicylates).

What to do

Discourage ginkgo during long-term high-dose salicylate therapy, and monitor for bleeding.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ginko biloba with Salicylates?

MediHelp rates the interaction as moderate. Ginko biloba and Salicylates can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Non-acetylated salicylates have weak antiplatelet effects, but at high doses can contribute to bleeding and GI irritation. Ginkgo may add slightly to the bleeding tendency.

How serious is the interaction between Ginko biloba and Salicylates?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Discourage ginkgo during long-term high-dose salicylate therapy, and monitor for bleeding.

What other medicines interact with Ginko biloba?

MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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