Drug interactions
Glibenclamide + Vanadium
Severity: Minor
Glibenclamide and Vanadium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vanadium compounds have insulin-mimetic properties and may lower blood glucose. Used together with glyburide, they could increase the risk of hypoglycemia.
What this interaction means in plain words
Glibenclamide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Insulin-mimetic and insulin-sensitizing actions of vanadium add to sulfonylurea effects.
What to do
Monitor blood glucose when vanadium supplements are taken with glyburide. Reduce the glyburide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glibenclamide
- Bosentan + Glibenclamide Contraindicated
- Cholic acid + Glibenclamide Major
- Ciprofloxacin + Glibenclamide Major
- Clarithromycin + Glibenclamide Major
- Fluconazole + Glibenclamide Major
- Glibenclamide + Insulin degludec-liraglutide Major
Frequently asked questions
Can I take Glibenclamide with Vanadium?
MediHelp rates the interaction as minor. Glibenclamide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vanadium compounds have insulin-mimetic properties and may lower blood glucose. Used together with glyburide, they could increase the risk of hypoglycemia.
How serious is the interaction between Glibenclamide and Vanadium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when vanadium supplements are taken with glyburide. Reduce the glyburide dose if hypoglycemia occurs.
What other medicines interact with Glibenclamide?
MediHelp also lists interactions of Glibenclamide with, for example, Bosentan, Cholic acid, Ciprofloxacin. The full list is on the Glibenclamide page.
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