Drug interactions
Gold sodium thiomalate + Meningococcal group b vaccine
Severity: Minor
Gold sodium thiomalate and Meningococcal group b vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gold salts can have immunomodulating effects, and patients on them for rheumatoid disease may mount a weaker antibody response to inactivated vaccines. The meningococcal B vaccine may therefore provide less protection than expected.
What this interaction means in plain words
Gold sodium thiomalate and Meningococcal group b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Immunomodulation by gold may blunt vaccine-induced antibody response; the effect is not well characterized.
What to do
Vaccinate according to schedule, as the inactivated vaccine is not contraindicated. Consider checking response or giving booster doses in patients at high risk of meningococcal disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Frequently asked questions
Can I take Gold sodium thiomalate with Meningococcal group b vaccine?
MediHelp rates the interaction as minor. Gold sodium thiomalate and Meningococcal group b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Gold salts can have immunomodulating effects, and patients on them for rheumatoid disease may mount a weaker antibody response to inactivated vaccines. The meningococcal B vaccine may therefore provide less protection than expected.
How serious is the interaction between Gold sodium thiomalate and Meningococcal group b vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate according to schedule, as the inactivated vaccine is not contraindicated. Consider checking response or giving booster doses in patients at high risk of meningococcal disease.
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