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Drug interactions

Gold sodium thiomalate + Olaparib

Severity: Moderate

Gold sodium thiomalate and Olaparib: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Olaparib commonly causes anemia, neutropenia and thrombocytopenia, and injectable gold can also suppress the bone marrow. Using them together may produce additive or more severe cytopenias.

What this interaction means in plain words

Gold sodium thiomalate and Olaparib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive myelosuppression through pharmacodynamic overlap.

What to do

Monitor complete blood counts regularly and adjust or interrupt olaparib per labeling if cytopenias develop. Consider stopping gold if marrow toxicity occurs.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Gold sodium thiomalate with Olaparib?

MediHelp rates the interaction as moderate. Gold sodium thiomalate and Olaparib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Olaparib commonly causes anemia, neutropenia and thrombocytopenia, and injectable gold can also suppress the bone marrow. Using them together may produce additive or more severe cytopenias.

How serious is the interaction between Gold sodium thiomalate and Olaparib?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts regularly and adjust or interrupt olaparib per labeling if cytopenias develop. Consider stopping gold if marrow toxicity occurs.

What other medicines interact with Olaparib?

MediHelp also lists interactions of Olaparib with, for example, Amiodarone, Amobarbital, Apalutamide. The full list is on the Olaparib page.

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