Drug interactions
Gold sodium thiomalate + Quinapril
Severity: Moderate
Gold sodium thiomalate and Quinapril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rare nitritoid reactions have been reported when injectable gold is given with ACE inhibitors, with flushing, nausea, vomiting and low blood pressure. The reaction may occur soon after injection and can be distressing or cause hypotension.
What this interaction means in plain words
Gold sodium thiomalate and Quinapril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
The mechanism is not firmly established; it may involve vasodilatory effects of gold with ACE inhibitor-related bradykinin potentiation.
What to do
Monitor blood pressure and symptoms after gold injections in patients on quinapril. If reactions recur, consider an alternative antihypertensive class.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Frequently asked questions
Can I take Gold sodium thiomalate with Quinapril?
MediHelp rates the interaction as moderate. Gold sodium thiomalate and Quinapril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rare nitritoid reactions have been reported when injectable gold is given with ACE inhibitors, with flushing, nausea, vomiting and low blood pressure. The reaction may occur soon after injection and can be distressing or cause hypotension.
How serious is the interaction between Gold sodium thiomalate and Quinapril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and symptoms after gold injections in patients on quinapril. If reactions recur, consider an alternative antihypertensive class.
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