Drug interactions
Green tea + Mestranol
Severity: Minor
Green tea and Mestranol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Estrogen-containing oral contraceptives reduce caffeine clearance, so caffeine from green tea may last longer and produce more stimulant effects. The effect is usually modest.
What this interaction means in plain words
Green tea and Mestranol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of CYP1A2-mediated caffeine metabolism by the estrogen.
What to do
No routine change is needed; suggest reducing tea intake if insomnia, tremor or palpitations develop.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Green tea
- Adenosine + Green tea Moderate
- Benzphetamine + Green tea Moderate
- Bortezomib + Green tea Moderate
- Dextroamphetamine + Green tea Moderate
- Diethylpropion + Green tea Moderate
- Ephedrine + Green tea Moderate
Frequently asked questions
Can I take Green tea with Mestranol?
MediHelp rates the interaction as minor. Green tea and Mestranol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Estrogen-containing oral contraceptives reduce caffeine clearance, so caffeine from green tea may last longer and produce more stimulant effects. The effect is usually modest.
How serious is the interaction between Green tea and Mestranol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; suggest reducing tea intake if insomnia, tremor or palpitations develop.
What other medicines interact with Green tea?
MediHelp also lists interactions of Green tea with, for example, Adenosine, Benzphetamine, Bortezomib. The full list is on the Green tea page.
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