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Drug interactions

Green tea + Selegiline transdermal

Severity: Moderate

Green tea and Selegiline transdermal: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Selegiline is an MAO inhibitor that can increase sensitivity to sympathomimetic substances. Caffeine in green tea may add to cardiovascular stimulation, with a risk of raised blood pressure or arrhythmia, particularly with large amounts.

What this interaction means in plain words

Green tea and Selegiline transdermal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive sympathomimetic stimulation from caffeine in the setting of MAO inhibition.

What to do

Limit green tea and other caffeine sources, and monitor blood pressure and heart rhythm. Counsel patients to report palpitations or severe headache.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Green tea with Selegiline transdermal?

MediHelp rates the interaction as moderate. Green tea and Selegiline transdermal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Selegiline is an MAO inhibitor that can increase sensitivity to sympathomimetic substances. Caffeine in green tea may add to cardiovascular stimulation, with a risk of raised blood pressure or arrhythmia, particularly with large amounts.

How serious is the interaction between Green tea and Selegiline transdermal?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit green tea and other caffeine sources, and monitor blood pressure and heart rhythm. Counsel patients to report palpitations or severe headache.

What other medicines interact with Green tea?

MediHelp also lists interactions of Green tea with, for example, Adenosine, Benzphetamine, Bortezomib. The full list is on the Green tea page.

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