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Drug interactions

Green tea + Yohimbine

Severity: Moderate

Green tea and Yohimbine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Yohimbine is an alpha-2 antagonist that can increase blood pressure, heart rate and anxiety. Caffeine in green tea adds to this stimulation, which may cause hypertension, palpitations and arrhythmias in susceptible patients.

What this interaction means in plain words

Green tea and Yohimbine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive sympathomimetic and CNS stimulation from caffeine and alpha-2 adrenergic blockade.

What to do

Limit green tea and other caffeine sources. Monitor blood pressure and heart rate, and avoid in patients with uncontrolled hypertension or arrhythmias.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Green tea with Yohimbine?

MediHelp rates the interaction as moderate. Green tea and Yohimbine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Yohimbine is an alpha-2 antagonist that can increase blood pressure, heart rate and anxiety. Caffeine in green tea adds to this stimulation, which may cause hypertension, palpitations and arrhythmias in susceptible patients.

How serious is the interaction between Green tea and Yohimbine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit green tea and other caffeine sources. Monitor blood pressure and heart rate, and avoid in patients with uncontrolled hypertension or arrhythmias.

What other medicines interact with Green tea?

MediHelp also lists interactions of Green tea with, for example, Adenosine, Benzphetamine, Bortezomib. The full list is on the Green tea page.

Full monographs, dosing and an interaction checker in the MediHelp app

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