Drug interactions
Heparin + Telmisartan
Severity: Moderate
Heparin and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Heparin, even in modest doses, can suppress aldosterone secretion, and telmisartan further limits aldosterone action. The combination can lead to hyperkalemia, especially with renal impairment, diabetes or prolonged heparin use.
What this interaction means in plain words
Heparin and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Heparin belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.
Why it happens
Heparin inhibits adrenal aldosterone synthesis, and ARB blockade adds to reduced renal potassium excretion.
What to do
Monitor serum potassium and creatinine during combined use, particularly beyond several days of heparin therapy. Treat hyperkalemia and avoid additional potassium-raising agents where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Heparin and Telmisartan, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Other interactions of Heparin
- Defibrotide + Heparin Contraindicated
- Heparin + Ketorolac Contraindicated
- Heparin + Oritavancin Contraindicated
- Acemetacin + Heparin Major
- Acetylsalicylic acid + Heparin Major
- Alteplase + Heparin Major
Frequently asked questions
Can I take Heparin with Telmisartan?
MediHelp rates the interaction as moderate. Heparin and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Heparin, even in modest doses, can suppress aldosterone secretion, and telmisartan further limits aldosterone action. The combination can lead to hyperkalemia, especially with renal impairment, diabetes or prolonged heparin use.
How serious is the interaction between Heparin and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and creatinine during combined use, particularly beyond several days of heparin therapy. Treat hyperkalemia and avoid additional potassium-raising agents where possible.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
