Drug interactions
Hepatitis A vaccine inactivated + Tralokinumab
Severity: Minor
Hepatitis A vaccine inactivated and Tralokinumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tralokinumab blocks IL-13, and its effect on responses to inactivated vaccines is not well studied. A clinically relevant reduction in hepatitis A vaccine response is considered unlikely.
What this interaction means in plain words
Hepatitis A vaccine inactivated and Tralokinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hepatitis A vaccine inactivated belongs to Anti Virals; Tralokinumab belongs to Miscellaneous.
Why it happens
IL-13 neutralization could theoretically modulate immune responses, but no established effect on inactivated vaccine immunogenicity.
What to do
Inactivated vaccines can be given during tralokinumab treatment. Complete vaccinations before starting therapy when practical.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hepatitis A vaccine inactivated
- Adalimumab + Hepatitis A vaccine inactivated Moderate
- Alefacept + Hepatitis A vaccine inactivated Moderate
- Anakinra + Hepatitis A vaccine inactivated Moderate
- Anti-thymocyte + Hepatitis A vaccine inactivated Moderate
- Antithymocyte globulin equine + Hepatitis A vaccine inactivated Moderate
- Antithymocyte globulin rabbit + Hepatitis A vaccine inactivated Moderate
Other interactions of Tralokinumab
Frequently asked questions
Can I take Hepatitis A vaccine inactivated with Tralokinumab?
MediHelp rates the interaction as minor. Hepatitis A vaccine inactivated and Tralokinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tralokinumab blocks IL-13, and its effect on responses to inactivated vaccines is not well studied. A clinically relevant reduction in hepatitis A vaccine response is considered unlikely.
How serious is the interaction between Hepatitis A vaccine inactivated and Tralokinumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Inactivated vaccines can be given during tralokinumab treatment. Complete vaccinations before starting therapy when practical.
What other medicines interact with Hepatitis A vaccine inactivated?
MediHelp also lists interactions of Hepatitis A vaccine inactivated with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Hepatitis A vaccine inactivated page.
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