Drug interactions
Horse chestnut seed + Ketorolac
Severity: Minor
Horse chestnut seed and Ketorolac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Horse chestnut contains aescin and may contain coumarin-like constituents, with a possible effect on coagulation. With ketorolac, bleeding risk may be additive, though documentation is sparse.
What this interaction means in plain words
Horse chestnut seed and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive effects on hemostasis; horse chestnut constituents may have weak antithrombotic activity, while ketorolac inhibits platelets.
What to do
Avoid horse chestnut supplements during ketorolac use where practical. Monitor for bleeding or bruising.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Horse chestnut seed with Ketorolac?
MediHelp rates the interaction as minor. Horse chestnut seed and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Horse chestnut contains aescin and may contain coumarin-like constituents, with a possible effect on coagulation. With ketorolac, bleeding risk may be additive, though documentation is sparse.
How serious is the interaction between Horse chestnut seed and Ketorolac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid horse chestnut supplements during ketorolac use where practical. Monitor for bleeding or bruising.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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