Drug interactions
Hydrochlorothiazide-olmesartan + Mometasone inhaled
Severity: Minor
Hydrochlorothiazide-olmesartan and Mometasone inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can promote potassium loss, and this may add to the hypokalemia caused by thiazides. With inhaled mometasone at usual doses, systemic exposure is low, so the clinical effect is small.
What this interaction means in plain words
Hydrochlorothiazide-olmesartan and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mineralocorticoid-related renal potassium wasting from systemically absorbed corticosteroid adds to thiazide-induced potassium loss.
What to do
No routine action is needed at usual inhaled doses. Check serum potassium if high doses are used or other potassium-lowering drugs are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Hydrochlorothiazide-olmesartan and Mometasone inhaled, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-olmesartan with Mometasone inhaled?
MediHelp rates the interaction as minor. Hydrochlorothiazide-olmesartan and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids can promote potassium loss, and this may add to the hypokalemia caused by thiazides. With inhaled mometasone at usual doses, systemic exposure is low, so the clinical effect is small.
How serious is the interaction between Hydrochlorothiazide-olmesartan and Mometasone inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed at usual inhaled doses. Check serum potassium if high doses are used or other potassium-lowering drugs are present.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
