Drug interactions
Hydrochlorothiazide-olmesartan + Pindolol
Severity: Minor
Hydrochlorothiazide-olmesartan and Pindolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pindolol is a beta-blocker that adds to the antihypertensive effect of olmesartan and hydrochlorothiazide. Excess hypotension or bradycardia can occur, and the combination is often used deliberately.
What this interaction means in plain words
Hydrochlorothiazide-olmesartan and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive effects via beta-blockade, angiotensin receptor blockade and diuresis.
What to do
Monitor blood pressure and heart rate when starting or changing doses. Reduce doses if symptomatic hypotension or bradycardia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-olmesartan with Pindolol?
MediHelp rates the interaction as minor. Hydrochlorothiazide-olmesartan and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pindolol is a beta-blocker that adds to the antihypertensive effect of olmesartan and hydrochlorothiazide. Excess hypotension or bradycardia can occur, and the combination is often used deliberately.
How serious is the interaction between Hydrochlorothiazide-olmesartan and Pindolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or changing doses. Reduce doses if symptomatic hypotension or bradycardia occurs.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
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