Drug interactions
Indapamide + Levosalbutamol
Severity: Moderate
Indapamide and Levosalbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can lower serum potassium, so combined use may cause clinically relevant hypokalemia, especially with high-dose or nebulized levosalbutamol. Hypokalemia raises the risk of arrhythmia.
What this interaction means in plain words
Indapamide and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indapamide belongs to Cardiovascular; Levosalbutamol belongs to Respiratory.
Why it happens
Beta-2 stimulation shifts potassium into cells, while indapamide increases renal potassium loss.
What to do
Monitor serum potassium and replace it as required. Pay particular attention in patients with cardiac disease or taking digoxin.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levosalbutamol
Other interactions of Indapamide
Frequently asked questions
Can I take Indapamide with Levosalbutamol?
MediHelp rates the interaction as moderate. Indapamide and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower serum potassium, so combined use may cause clinically relevant hypokalemia, especially with high-dose or nebulized levosalbutamol. Hypokalemia raises the risk of arrhythmia.
How serious is the interaction between Indapamide and Levosalbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and replace it as required. Pay particular attention in patients with cardiac disease or taking digoxin.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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