Drug interactions
Indapamide + Shark cartilage
Severity: Minor
Indapamide and Shark cartilage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide-type diuretics reduce urinary calcium excretion and can raise serum calcium. Shark cartilage has been reported to contain calcium and may theoretically contribute to hypercalcemia, although data are limited.
What this interaction means in plain words
Indapamide and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Reduced renal calcium excretion from indapamide combined with possible calcium content of the supplement.
What to do
Check serum calcium if the supplement is taken regularly with indapamide, and stop it if hypercalcemia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indapamide
Frequently asked questions
Can I take Indapamide with Shark cartilage?
MediHelp rates the interaction as minor. Indapamide and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide-type diuretics reduce urinary calcium excretion and can raise serum calcium. Shark cartilage has been reported to contain calcium and may theoretically contribute to hypercalcemia, although data are limited.
How serious is the interaction between Indapamide and Shark cartilage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum calcium if the supplement is taken regularly with indapamide, and stop it if hypercalcemia develops.
What other medicines interact with Indapamide?
MediHelp also lists interactions of Indapamide with, for example, Adagrasib, Amifostine, Amiodarone. The full list is on the Indapamide page.
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