Drug interactions
Indapamide + Terbutaline
Severity: Moderate
Indapamide and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower serum potassium, so combined use can cause hypokalemia and raise arrhythmic risk. Indapamide may also contribute to QT prolongation when potassium is low.
What this interaction means in plain words
Indapamide and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indapamide belongs to Cardiovascular; Terbutaline belongs to Respiratory.
Why it happens
Additive hypokalemia from beta-2 mediated intracellular potassium shift and thiazide-like diuretic renal potassium loss.
What to do
Monitor serum potassium and replace it as needed, especially in patients with cardiac disease or on digoxin.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Other interactions of Indapamide
Frequently asked questions
Can I take Indapamide with Terbutaline?
MediHelp rates the interaction as moderate. Indapamide and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower serum potassium, so combined use can cause hypokalemia and raise arrhythmic risk. Indapamide may also contribute to QT prolongation when potassium is low.
How serious is the interaction between Indapamide and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and replace it as needed, especially in patients with cardiac disease or on digoxin.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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