Drug interactions
Inotuzumab + Salbutamol
Severity: Moderate
Inotuzumab and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inotuzumab ozogamicin is associated with QT prolongation, and salbutamol may add to this effect, particularly if hypokalemia occurs. Risk is greatest in patients with other QT-prolonging factors.
What this interaction means in plain words
Inotuzumab and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-agonist hypokalemia as a possible contributor.
What to do
Perform ECG and electrolyte monitoring during treatment and correct potassium and magnesium abnormalities. Limit salbutamol to the lowest effective dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Frequently asked questions
Can I take Inotuzumab with Salbutamol?
MediHelp rates the interaction as moderate. Inotuzumab and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Inotuzumab ozogamicin is associated with QT prolongation, and salbutamol may add to this effect, particularly if hypokalemia occurs. Risk is greatest in patients with other QT-prolonging factors.
How serious is the interaction between Inotuzumab and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform ECG and electrolyte monitoring during treatment and correct potassium and magnesium abnormalities. Limit salbutamol to the lowest effective dose.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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