Drug interactions
Insulin aspart + Oxymetholone
Severity: Moderate
Insulin aspart and Oxymetholone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxymetholone can reduce blood glucose and increase insulin sensitivity, so insulin requirements may decrease. Hypoglycemia can occur if the insulin dose is not adjusted.
What this interaction means in plain words
Insulin aspart and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anabolic androgens increase insulin sensitivity and alter glucose metabolism, giving an additive hypoglycemic effect.
What to do
Monitor blood glucose closely when oxymetholone is started or stopped, and reduce the insulin dose as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin aspart
Frequently asked questions
Can I take Insulin aspart with Oxymetholone?
MediHelp rates the interaction as moderate. Insulin aspart and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxymetholone can reduce blood glucose and increase insulin sensitivity, so insulin requirements may decrease. Hypoglycemia can occur if the insulin dose is not adjusted.
How serious is the interaction between Insulin aspart and Oxymetholone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when oxymetholone is started or stopped, and reduce the insulin dose as needed.
What other medicines interact with Insulin aspart?
MediHelp also lists interactions of Insulin aspart with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin aspart page.
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