Drug interactions
Insulin aspart-insulin aspart protamine + Olmesartan
Severity: Minor
Insulin aspart-insulin aspart protamine and Olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olmesartan may slightly improve insulin sensitivity and enhance the effect of insulin, with a small increase in hypoglycemia risk.
What this interaction means in plain words
Insulin aspart-insulin aspart protamine and Olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Insulin aspart-insulin aspart protamine belongs to Endocrine; Olmesartan belongs to Cardiovascular.
Why it happens
ARBs may enhance insulin sensitivity; the mechanism is not fully established.
What to do
Monitor glucose more often after starting olmesartan. Reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin aspart-insulin aspart protamine
- Ethanol + Insulin aspart-insulin aspart protamine Major
- Insulin aspart-insulin aspart protamine + Pentamidine Major
- Insulin aspart-insulin aspart protamine + Pioglitazone Major
- Insulin aspart-insulin aspart protamine + Rosiglitazone Major
- Acarbose + Insulin aspart-insulin aspart protamine Moderate
- Albiglutide + Insulin aspart-insulin aspart protamine Moderate
Other interactions of Olmesartan
- Aliskiren + Olmesartan Contraindicated
- Olmesartan + Sparsentan Contraindicated
- Aldesleukin + Olmesartan Major
- Amifostine + Olmesartan Major
- Amiloride + Olmesartan Major
- Amlodipine-benazepril + Olmesartan Major
Frequently asked questions
Can I take Insulin aspart-insulin aspart protamine with Olmesartan?
MediHelp rates the interaction as minor. Insulin aspart-insulin aspart protamine and Olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Olmesartan may slightly improve insulin sensitivity and enhance the effect of insulin, with a small increase in hypoglycemia risk.
How serious is the interaction between Insulin aspart-insulin aspart protamine and Olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose more often after starting olmesartan. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin aspart-insulin aspart protamine?
MediHelp also lists interactions of Insulin aspart-insulin aspart protamine with, for example, Ethanol, Pentamidine, Pioglitazone. The full list is on the Insulin aspart-insulin aspart protamine page.
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