Drug interactions
Insulin aspart protamine / insulin aspart + Telmisartan
Severity: Moderate
Insulin aspart protamine / insulin aspart and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers can enhance insulin sensitivity and may increase the glucose-lowering effect of insulin. This can occasionally lead to hypoglycemia, particularly when the ARB is first started.
What this interaction means in plain words
Insulin aspart protamine / insulin aspart and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effect, probably through improved insulin sensitivity and glucose uptake with ARBs.
What to do
Monitor blood glucose more frequently when telmisartan is started, changed or stopped. Reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Frequently asked questions
Can I take Insulin aspart protamine / insulin aspart with Telmisartan?
MediHelp rates the interaction as moderate. Insulin aspart protamine / insulin aspart and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Angiotensin receptor blockers can enhance insulin sensitivity and may increase the glucose-lowering effect of insulin. This can occasionally lead to hypoglycemia, particularly when the ARB is first started.
How serious is the interaction between Insulin aspart protamine / insulin aspart and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when telmisartan is started, changed or stopped. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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