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Drug interactions

Insulin detemir + Oxymetholone

Severity: Moderate

Insulin detemir and Oxymetholone: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oxymetholone is an anabolic steroid that can increase insulin sensitivity and lower glucose levels. Used with insulin detemir it may cause hypoglycemia, and the label for anabolic steroids advises watching diabetic patients for altered insulin requirements.

What this interaction means in plain words

Insulin detemir and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Anabolic steroids enhance insulin sensitivity and glucose uptake, adding to the glucose-lowering effect of insulin.

What to do

Monitor blood glucose closely when oxymetholone is started or stopped. Reduce the insulin detemir dose as needed to prevent hypoglycemia.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Insulin detemir with Oxymetholone?

MediHelp rates the interaction as moderate. Insulin detemir and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxymetholone is an anabolic steroid that can increase insulin sensitivity and lower glucose levels. Used with insulin detemir it may cause hypoglycemia, and the label for anabolic steroids advises watching diabetic patients for altered insulin requirements.

How serious is the interaction between Insulin detemir and Oxymetholone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when oxymetholone is started or stopped. Reduce the insulin detemir dose as needed to prevent hypoglycemia.

What other medicines interact with Insulin detemir?

MediHelp also lists interactions of Insulin detemir with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin detemir page.

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