Drug interactions
Insulin detemir + Sulfadiazine
Severity: Moderate
Insulin detemir and Sulfadiazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sulfonamide antibiotics can lower blood glucose and may add to the effect of insulin, causing hypoglycemia. The risk is greater in renal impairment or poor oral intake.
What this interaction means in plain words
Insulin detemir and Sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Sulfonamides may stimulate insulin secretion and have additive hypoglycemic effects.
What to do
Monitor blood glucose during sulfadiazine therapy and reduce insulin detemir if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Insulin detemir and Sulfadiazine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Insulin detemir
Frequently asked questions
Can I take Insulin detemir with Sulfadiazine?
MediHelp rates the interaction as moderate. Insulin detemir and Sulfadiazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sulfonamide antibiotics can lower blood glucose and may add to the effect of insulin, causing hypoglycemia. The risk is greater in renal impairment or poor oral intake.
How serious is the interaction between Insulin detemir and Sulfadiazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during sulfadiazine therapy and reduce insulin detemir if hypoglycemia occurs.
What other medicines interact with Insulin detemir?
MediHelp also lists interactions of Insulin detemir with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin detemir page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
