Drug interactions
Insulin lispro + Maitake
Severity: Minor
Insulin lispro and Maitake: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom extracts have lowered blood glucose in animal studies, so additive hypoglycemia with insulin is theoretically possible. Human data are limited.
What this interaction means in plain words
Insulin lispro and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible improvement in insulin sensitivity based on animal data; not established in humans.
What to do
Monitor blood glucose when maitake supplements are started and reduce insulin if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin lispro
Frequently asked questions
Can I take Insulin lispro with Maitake?
MediHelp rates the interaction as minor. Insulin lispro and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom extracts have lowered blood glucose in animal studies, so additive hypoglycemia with insulin is theoretically possible. Human data are limited.
How serious is the interaction between Insulin lispro and Maitake?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when maitake supplements are started and reduce insulin if hypoglycemia occurs.
What other medicines interact with Insulin lispro?
MediHelp also lists interactions of Insulin lispro with, for example, Alogliptin-pioglitazone, Ethanol, Metreleptin. The full list is on the Insulin lispro page.
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