Drug interactions
Insulin lispro + Oxymetholone
Severity: Moderate
Insulin lispro and Oxymetholone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxymetholone, an anabolic steroid, can enhance insulin sensitivity and lower blood glucose. When given with insulin lispro, hypoglycemia may occur and insulin needs may fall.
What this interaction means in plain words
Insulin lispro and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypoglycemic effect resulting from improved insulin sensitivity and altered glucose metabolism caused by the anabolic steroid.
What to do
Check blood glucose more frequently after starting or changing oxymetholone. Lower the insulin lispro dose if glucose readings fall.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin lispro
Frequently asked questions
Can I take Insulin lispro with Oxymetholone?
MediHelp rates the interaction as moderate. Insulin lispro and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxymetholone, an anabolic steroid, can enhance insulin sensitivity and lower blood glucose. When given with insulin lispro, hypoglycemia may occur and insulin needs may fall.
How serious is the interaction between Insulin lispro and Oxymetholone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose more frequently after starting or changing oxymetholone. Lower the insulin lispro dose if glucose readings fall.
What other medicines interact with Insulin lispro?
MediHelp also lists interactions of Insulin lispro with, for example, Alogliptin-pioglitazone, Ethanol, Metreleptin. The full list is on the Insulin lispro page.
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