Drug interactions
Insulin regular human + Isoniazid
Severity: Minor
Insulin regular human and Isoniazid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Isoniazid has been associated with disturbances in glycemic control in people with diabetes, and tuberculosis itself can alter insulin requirements. Insulin needs may rise in some patients, though the effect is inconsistent.
What this interaction means in plain words
Insulin regular human and Isoniazid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
The mechanism is not well established.
What to do
Monitor blood glucose more frequently when starting or stopping isoniazid and adjust insulin dose accordingly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Isoniazid
Frequently asked questions
Can I take Insulin regular human with Isoniazid?
MediHelp rates the interaction as minor. Insulin regular human and Isoniazid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Isoniazid has been associated with disturbances in glycemic control in people with diabetes, and tuberculosis itself can alter insulin requirements. Insulin needs may rise in some patients, though the effect is inconsistent.
How serious is the interaction between Insulin regular human and Isoniazid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when starting or stopping isoniazid and adjust insulin dose accordingly.
What other medicines interact with Isoniazid?
MediHelp also lists interactions of Isoniazid with, for example, Bacillus calmette-guerin substrain tice, Benzhydrocodone / acetaminophen, Carbamazepine. The full list is on the Isoniazid page.
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