Drug interactions
Iodinated glycerol + Lithium
Severity: Moderate
Iodinated glycerol and Lithium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both lithium and iodine-containing agents can suppress thyroid hormone production, so together they may add to the risk of hypothyroidism and goiter. The effect is more likely with prolonged use.
What this interaction means in plain words
Iodinated glycerol and Lithium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive inhibition of thyroid hormone synthesis and release.
What to do
Monitor TSH and thyroid hormone levels periodically during combined use. Consider an alternative expectorant if thyroid dysfunction develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Lithium
- Lithium + Thioridazine Contraindicated
- Lithium + Vandetanib Contraindicated
- Aceclofenac + Lithium Major
- Acemetacin + Lithium Major
- Amisulpride + Lithium Major
- Amlodipine-benazepril + Lithium Major
Frequently asked questions
Can I take Iodinated glycerol with Lithium?
MediHelp rates the interaction as moderate. Iodinated glycerol and Lithium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both lithium and iodine-containing agents can suppress thyroid hormone production, so together they may add to the risk of hypothyroidism and goiter. The effect is more likely with prolonged use.
How serious is the interaction between Iodinated glycerol and Lithium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor TSH and thyroid hormone levels periodically during combined use. Consider an alternative expectorant if thyroid dysfunction develops.
What other medicines interact with Lithium?
MediHelp also lists interactions of Lithium with, for example, Thioridazine, Vandetanib, Aceclofenac. The full list is on the Lithium page.
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