Drug interactions
Iron dextran complex + Rabeprazole
Severity: Minor
Iron dextran complex and Rabeprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rabeprazole raises gastric pH, which can reduce absorption of oral iron preparations. Iron dextran is mostly given parenterally, where gastric pH does not matter. An effect would be relevant only for oral iron products.
What this interaction means in plain words
Iron dextran complex and Rabeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Reduced gastric acid impairs dissolution and absorption of oral iron.
What to do
If oral iron is used, monitor hemoglobin and ferritin on long-term PPI therapy. No action is needed for parenteral iron dextran.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Iron dextran complex and Rabeprazole, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Rabeprazole
- Rabeprazole + Rilpivirine Contraindicated
- Acalabrutinib + Rabeprazole Major
- Atazanavir + Rabeprazole Major
- Dacomitinib + Rabeprazole Major
- Dasatinib + Rabeprazole Major
- Erlotinib + Rabeprazole Major
Frequently asked questions
Can I take Iron dextran complex with Rabeprazole?
MediHelp rates the interaction as minor. Iron dextran complex and Rabeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rabeprazole raises gastric pH, which can reduce absorption of oral iron preparations. Iron dextran is mostly given parenterally, where gastric pH does not matter. An effect would be relevant only for oral iron products.
How serious is the interaction between Iron dextran complex and Rabeprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If oral iron is used, monitor hemoglobin and ferritin on long-term PPI therapy. No action is needed for parenteral iron dextran.
What other medicines interact with Rabeprazole?
MediHelp also lists interactions of Rabeprazole with, for example, Rilpivirine, Acalabrutinib, Atazanavir. The full list is on the Rabeprazole page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
