Drug interactions
Isradipine + Olanzapine
Severity: Minor
Isradipine and Olanzapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Isradipine is not an established QT-prolonging drug, so the QT concern is weak. The more relevant effect is additive hypotension, since both drugs can lower blood pressure and cause dizziness.
What this interaction means in plain words
Isradipine and Olanzapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive hypotensive effects from calcium channel blockade and alpha-adrenergic antagonism.
What to do
Monitor blood pressure and orthostatic symptoms when starting or changing doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Olanzapine
Frequently asked questions
Can I take Isradipine with Olanzapine?
MediHelp rates the interaction as minor. Isradipine and Olanzapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Isradipine is not an established QT-prolonging drug, so the QT concern is weak. The more relevant effect is additive hypotension, since both drugs can lower blood pressure and cause dizziness.
How serious is the interaction between Isradipine and Olanzapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when starting or changing doses.
What other medicines interact with Olanzapine?
MediHelp also lists interactions of Olanzapine with, for example, Amisulpride, Amoxapine, Apomorphine. The full list is on the Olanzapine page.
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