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Drug interactions

Ketorolac + Metaproterenol

Severity: Minor

Ketorolac and Metaproterenol: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Metaproterenol can lower serum potassium, while NSAIDs may raise it through reduced renal excretion. The opposing effects make a meaningful clinical interaction unlikely.

What this interaction means in plain words

Ketorolac and Metaproterenol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Opposing effects on potassium: beta-agonist cellular uptake versus NSAID-related reduced renal potassium excretion.

What to do

No routine action is needed. Monitor potassium in patients with renal impairment or on high doses.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ketorolac with Metaproterenol?

MediHelp rates the interaction as minor. Ketorolac and Metaproterenol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Metaproterenol can lower serum potassium, while NSAIDs may raise it through reduced renal excretion. The opposing effects make a meaningful clinical interaction unlikely.

How serious is the interaction between Ketorolac and Metaproterenol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor potassium in patients with renal impairment or on high doses.

What other medicines interact with Ketorolac?

MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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