Drug interactions
Ketorolac + Mipomersen
Severity: Minor
Ketorolac and Mipomersen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mipomersen commonly raises transaminases and causes hepatic fat accumulation, and NSAIDs can occasionally cause liver injury. Using both may add to hepatic stress, although the interaction is largely theoretical.
What this interaction means in plain words
Ketorolac and Mipomersen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive potential hepatotoxicity; no pharmacokinetic interaction is established.
What to do
Monitor liver enzymes according to mipomersen labeling and review therapy if transaminases rise during ketorolac use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Ketorolac with Mipomersen?
MediHelp rates the interaction as minor. Ketorolac and Mipomersen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mipomersen commonly raises transaminases and causes hepatic fat accumulation, and NSAIDs can occasionally cause liver injury. Using both may add to hepatic stress, although the interaction is largely theoretical.
How serious is the interaction between Ketorolac and Mipomersen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor liver enzymes according to mipomersen labeling and review therapy if transaminases rise during ketorolac use.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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