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Drug interactions

Ketorolac + Noni juice

Severity: Minor

Ketorolac and Noni juice: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Noni juice contains a substantial amount of potassium, and ketorolac can reduce renal potassium excretion. Together they may contribute to hyperkalemia, mainly in patients with renal impairment or those taking other potassium-raising drugs.

What this interaction means in plain words

Ketorolac and Noni juice have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Dietary potassium load combined with NSAID-induced suppression of renin-aldosterone and reduced renal potassium excretion.

What to do

Avoid regular noni juice intake in patients with kidney disease receiving ketorolac, and check serum potassium if both are used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ketorolac with Noni juice?

MediHelp rates the interaction as minor. Ketorolac and Noni juice have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Noni juice contains a substantial amount of potassium, and ketorolac can reduce renal potassium excretion. Together they may contribute to hyperkalemia, mainly in patients with renal impairment or those taking other potassium-raising drugs.

How serious is the interaction between Ketorolac and Noni juice?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular noni juice intake in patients with kidney disease receiving ketorolac, and check serum potassium if both are used.

What other medicines interact with Ketorolac?

MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.

Full monographs, dosing and an interaction checker in the MediHelp app

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