Drug interactions
Ketorolac + Pau d'arco
Severity: Minor
Ketorolac and Pau d'arco: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pau d'arco contains naphthoquinones such as lapachol that may interfere with vitamin K and coagulation. This may theoretically add to ketorolac's bleeding risk, though no solid clinical data exist.
What this interaction means in plain words
Ketorolac and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive effect on hemostasis through vitamin K antagonism by lapachol and platelet inhibition by ketorolac.
What to do
Advise avoiding pau d'arco products during ketorolac therapy and monitor for bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Ketorolac with Pau d'arco?
MediHelp rates the interaction as minor. Ketorolac and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pau d'arco contains naphthoquinones such as lapachol that may interfere with vitamin K and coagulation. This may theoretically add to ketorolac's bleeding risk, though no solid clinical data exist.
How serious is the interaction between Ketorolac and Pau d'arco?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding pau d'arco products during ketorolac therapy and monitor for bleeding.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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