Drug interactions
Ketorolac + Phytoestrogens
Severity: Minor
Ketorolac and Phytoestrogens: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phytoestrogens such as isoflavones have mild antiplatelet activity in vitro. A clinically relevant bleeding interaction with ketorolac is theoretical and unproven.
What this interaction means in plain words
Ketorolac and Phytoestrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak additive antiplatelet effect; not established clinically.
What to do
No routine change is needed; monitor for unusual bruising or bleeding during ketorolac therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Ketorolac with Phytoestrogens?
MediHelp rates the interaction as minor. Ketorolac and Phytoestrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Phytoestrogens such as isoflavones have mild antiplatelet activity in vitro. A clinically relevant bleeding interaction with ketorolac is theoretical and unproven.
How serious is the interaction between Ketorolac and Phytoestrogens?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor for unusual bruising or bleeding during ketorolac therapy.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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