Drug interactions
Ketorolac + Temocillin
Severity: Minor
Ketorolac and Temocillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are cleared by renal tubular secretion and are highly protein bound, so ketorolac could modestly raise temocillin exposure. Clinical significance is likely small. Ketorolac may also add renal stress in ill patients.
What this interaction means in plain words
Ketorolac and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible competition for renal tubular secretion and protein binding.
What to do
No dose adjustment is usually needed. Monitor renal function in patients with renal impairment or dehydration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Ketorolac with Temocillin?
MediHelp rates the interaction as minor. Ketorolac and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are cleared by renal tubular secretion and are highly protein bound, so ketorolac could modestly raise temocillin exposure. Clinical significance is likely small. Ketorolac may also add renal stress in ill patients.
How serious is the interaction between Ketorolac and Temocillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed. Monitor renal function in patients with renal impairment or dehydration.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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