Drug interactions
Lansoprazole + Polysaccharide iron
Severity: Minor
Lansoprazole and Polysaccharide iron: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reduced gastric acidity may impair absorption of oral iron. Polysaccharide iron is less dependent on acid than iron salts, but efficacy may still fall with prolonged PPI use.
What this interaction means in plain words
Lansoprazole and Polysaccharide iron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Higher gastric pH decreases iron solubility and absorption.
What to do
Monitor hemoglobin and ferritin during long-term co-therapy and consider parenteral iron if response is poor.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lansoprazole
- Lansoprazole + Mavacamten Contraindicated
- Lansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Lansoprazole Major
- Atazanavir + Lansoprazole Major
- Dacomitinib + Lansoprazole Major
- Dasatinib + Lansoprazole Major
Frequently asked questions
Can I take Lansoprazole with Polysaccharide iron?
MediHelp rates the interaction as minor. Lansoprazole and Polysaccharide iron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced gastric acidity may impair absorption of oral iron. Polysaccharide iron is less dependent on acid than iron salts, but efficacy may still fall with prolonged PPI use.
How serious is the interaction between Lansoprazole and Polysaccharide iron?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and ferritin during long-term co-therapy and consider parenteral iron if response is poor.
What other medicines interact with Lansoprazole?
MediHelp also lists interactions of Lansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Lansoprazole page.
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