Drug interactions
Lansoprazole + Thyroid desiccated
Severity: Minor
Lansoprazole and Thyroid desiccated: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reduced gastric acidity from lansoprazole may decrease absorption of oral desiccated thyroid. Evidence is mixed, but some patients show rising TSH.
What this interaction means in plain words
Lansoprazole and Thyroid desiccated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Higher gastric pH may impair dissolution and absorption of oral thyroid hormone.
What to do
Check TSH after starting or stopping lansoprazole and adjust the thyroid dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lansoprazole
- Lansoprazole + Mavacamten Contraindicated
- Lansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Lansoprazole Major
- Atazanavir + Lansoprazole Major
- Dacomitinib + Lansoprazole Major
- Dasatinib + Lansoprazole Major
Frequently asked questions
Can I take Lansoprazole with Thyroid desiccated?
MediHelp rates the interaction as minor. Lansoprazole and Thyroid desiccated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced gastric acidity from lansoprazole may decrease absorption of oral desiccated thyroid. Evidence is mixed, but some patients show rising TSH.
How serious is the interaction between Lansoprazole and Thyroid desiccated?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check TSH after starting or stopping lansoprazole and adjust the thyroid dose if needed.
What other medicines interact with Lansoprazole?
MediHelp also lists interactions of Lansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Lansoprazole page.
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