Drug interactions
Levobetaxolol + Propranolol
Severity: Moderate
Levobetaxolol and Propranolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levobetaxolol is an ophthalmic beta-blocker that is partly absorbed systemically. Combined with oral propranolol it can add to systemic beta-blockade, causing bradycardia, hypotension or bronchospasm.
What this interaction means in plain words
Levobetaxolol and Propranolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic receptor blockade.
What to do
Avoid duplicate beta-blockade where possible. If both are needed, monitor heart rate, blood pressure and respiratory status.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Albuterol + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
Frequently asked questions
Can I take Levobetaxolol with Propranolol?
MediHelp rates the interaction as moderate. Levobetaxolol and Propranolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Levobetaxolol is an ophthalmic beta-blocker that is partly absorbed systemically. Combined with oral propranolol it can add to systemic beta-blockade, causing bradycardia, hypotension or bronchospasm.
How serious is the interaction between Levobetaxolol and Propranolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid duplicate beta-blockade where possible. If both are needed, monitor heart rate, blood pressure and respiratory status.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
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