Drug interactions
Levosalbutamol + Pimozide
Severity: Moderate
Levosalbutamol and Pimozide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta-2 agonists can cause hypokalemia and tachycardia, while pimozide prolongs the QT interval and carries a risk of torsades de pointes. Combined use may raise arrhythmic risk, particularly with higher doses of the beta agonist.
What this interaction means in plain words
Levosalbutamol and Pimozide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levosalbutamol belongs to Respiratory; Pimozide belongs to Central Nervous System.
Why it happens
Beta-agonist-induced hypokalemia and QT effects add to pimozide's QT prolongation.
What to do
Check serum potassium and magnesium and obtain an ECG if high or frequent bronchodilator doses are needed. Correct electrolyte disturbances before and during co-therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Levosalbutamol and Pimozide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Levosalbutamol
Other interactions of Pimozide
- Adagrasib + Pimozide Contraindicated
- Amiodarone + Pimozide Contraindicated
- Amisulpride + Pimozide Contraindicated
- Amitriptyline + Pimozide Contraindicated
- Amoxapine + Pimozide Contraindicated
- Anagrelide + Pimozide Contraindicated
Frequently asked questions
Can I take Levosalbutamol with Pimozide?
MediHelp rates the interaction as moderate. Levosalbutamol and Pimozide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Beta-2 agonists can cause hypokalemia and tachycardia, while pimozide prolongs the QT interval and carries a risk of torsades de pointes. Combined use may raise arrhythmic risk, particularly with higher doses of the beta agonist.
How serious is the interaction between Levosalbutamol and Pimozide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium and magnesium and obtain an ECG if high or frequent bronchodilator doses are needed. Correct electrolyte disturbances before and during co-therapy.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
