Drug interactions
Levosalbutamol + Saquinavir
Severity: Moderate
Levosalbutamol and Saquinavir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Saquinavir prolongs the QT interval, and levosalbutamol can cause hypokalemia and tachycardia, which may further raise arrhythmia risk. The combination could precipitate torsades de pointes in susceptible patients.
What this interaction means in plain words
Levosalbutamol and Saquinavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia increasing proarrhythmic risk.
What to do
Obtain a baseline ECG and correct potassium and magnesium; monitor QTc and use caution in patients with other QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levosalbutamol
Frequently asked questions
Can I take Levosalbutamol with Saquinavir?
MediHelp rates the interaction as moderate. Levosalbutamol and Saquinavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Saquinavir prolongs the QT interval, and levosalbutamol can cause hypokalemia and tachycardia, which may further raise arrhythmia risk. The combination could precipitate torsades de pointes in susceptible patients.
How serious is the interaction between Levosalbutamol and Saquinavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct potassium and magnesium; monitor QTc and use caution in patients with other QT risk factors.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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