Drug interactions
Levosalbutamol + Terbutaline
Severity: Moderate
Levosalbutamol and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Using two beta-2 agonists together adds up their effects, including tachycardia, tremor, raised blood pressure and a fall in serum potassium. This is a therapeutic duplication that raises the chance of arrhythmia, especially in patients with cardiac disease or hypoxia.
What this interaction means in plain words
Levosalbutamol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levosalbutamol belongs to Respiratory; Terbutaline belongs to Respiratory.
Why it happens
Additive beta-adrenergic stimulation, with beta-2 mediated intracellular potassium shift and cardiac stimulation.
What to do
Avoid routine concurrent use of two beta-2 agonists and use a single agent at the lowest effective dose. If both are given, monitor heart rate, blood pressure and serum potassium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levosalbutamol
Other interactions of Terbutaline
Frequently asked questions
Can I take Levosalbutamol with Terbutaline?
MediHelp rates the interaction as moderate. Levosalbutamol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Using two beta-2 agonists together adds up their effects, including tachycardia, tremor, raised blood pressure and a fall in serum potassium. This is a therapeutic duplication that raises the chance of arrhythmia, especially in patients with cardiac disease or hypoxia.
How serious is the interaction between Levosalbutamol and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine concurrent use of two beta-2 agonists and use a single agent at the lowest effective dose. If both are given, monitor heart rate, blood pressure and serum potassium.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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