Drug interactions
Levosalbutamol + Yohimbine
Severity: Moderate
Levosalbutamol and Yohimbine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs raise sympathetic activity, so combining them may increase heart rate and blood pressure and provoke palpitations, tremor or anxiety. Patients with hypertension, arrhythmia or coronary disease are at greater risk.
What this interaction means in plain words
Levosalbutamol and Yohimbine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic stimulation: beta-2 agonism from levosalbutamol plus alpha-2 antagonism that increases noradrenaline release from yohimbine.
What to do
Monitor blood pressure and heart rate, and avoid the combination in uncontrolled hypertension or significant cardiac disease. Reduce doses or stop yohimbine if symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levosalbutamol
Frequently asked questions
Can I take Levosalbutamol with Yohimbine?
MediHelp rates the interaction as moderate. Levosalbutamol and Yohimbine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs raise sympathetic activity, so combining them may increase heart rate and blood pressure and provoke palpitations, tremor or anxiety. Patients with hypertension, arrhythmia or coronary disease are at greater risk.
How serious is the interaction between Levosalbutamol and Yohimbine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, and avoid the combination in uncontrolled hypertension or significant cardiac disease. Reduce doses or stop yohimbine if symptoms occur.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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