Drug interactions
Lily of the valley + Telmisartan-amlodipine
Severity: Moderate
Lily of the valley and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lily of the valley contains cardiac glycosides. If the product contains a thiazide, potassium depletion could increase the risk of glycoside-induced arrhythmias. Telmisartan itself tends to raise potassium.
What this interaction means in plain words
Lily of the valley and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Hypokalemia from any thiazide component sensitizes the myocardium to cardiac glycoside toxicity.
What to do
Avoid lily of the valley preparations. If exposure occurs, check serum potassium and ECG and seek toxicology advice.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Frequently asked questions
Can I take Lily of the valley with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Lily of the valley and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lily of the valley contains cardiac glycosides. If the product contains a thiazide, potassium depletion could increase the risk of glycoside-induced arrhythmias. Telmisartan itself tends to raise potassium.
How serious is the interaction between Lily of the valley and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid lily of the valley preparations. If exposure occurs, check serum potassium and ECG and seek toxicology advice.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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