Drug interactions
Lonapegsomatropin + Theophylline
Severity: Minor
Lonapegsomatropin and Theophylline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase the activity of some cytochrome P450 enzymes, which could lower theophylline concentrations. The evidence is limited and the effect is probably small.
What this interaction means in plain words
Lonapegsomatropin and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lonapegsomatropin belongs to Endocrine; Theophylline belongs to Respiratory.
Why it happens
Growth hormone may induce CYP-mediated clearance, including CYP1A2 and CYP3A4.
What to do
Monitor theophylline response and serum levels after starting lonapegsomatropin, adjusting the dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Theophylline
- Riociguat + Theophylline Contraindicated
- Adenosine + Theophylline Major
- Apalutamide + Theophylline Major
- Bupropion + Theophylline Major
- Carvedilol + Theophylline Major
- Cimetidine + Theophylline Major
Other interactions of Lonapegsomatropin
Frequently asked questions
Can I take Lonapegsomatropin with Theophylline?
MediHelp rates the interaction as minor. Lonapegsomatropin and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase the activity of some cytochrome P450 enzymes, which could lower theophylline concentrations. The evidence is limited and the effect is probably small.
How serious is the interaction between Lonapegsomatropin and Theophylline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor theophylline response and serum levels after starting lonapegsomatropin, adjusting the dose if needed.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
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