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Drug interactions

Maitake + Metformin

Severity: Minor

Maitake and Metformin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Maitake mushroom extracts lowered blood glucose in animal studies and may theoretically add to metformin's effect. Human data are scarce.

What this interaction means in plain words

Maitake and Metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive glucose-lowering effect (pharmacodynamic), based on animal data.

What to do

Monitor blood glucose if maitake supplements are used and adjust therapy if values fall.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Maitake with Metformin?

MediHelp rates the interaction as minor. Maitake and Metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom extracts lowered blood glucose in animal studies and may theoretically add to metformin's effect. Human data are scarce.

How serious is the interaction between Maitake and Metformin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if maitake supplements are used and adjust therapy if values fall.

What other medicines interact with Metformin?

MediHelp also lists interactions of Metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Metformin page.

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